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Aref Al-Kali: New concept and potential biological subgroup for relapsed or refractory AML
Feb 2, 2025, 01:37

Aref Al-Kali: New concept and potential biological subgroup for relapsed or refractory AML

Aref Al-Kali, Hematologist/Oncologist at Mayo Clinic, shared a post on X, adding:

“I mentioned this abstract a year ago. Now published in Blood Journal.

New concept and potential biological subgroup -RUNX1- that benefit the most.”

A phase 1 study of the amino acid modulator pegcrisantaspase and venetoclax for relapsed or refractory acute myeloid leukemia

Authors: Yuchen Liu et al.

Aref Al-Kali: New concept and potential biological subgroup for relapsed or refractory AML

Quoting his original post:

“PegC plus VEN in patients with rrAML has activity esp in RUNX1m. Excellent work and new front on targeting oncometabolome.”

Aref Al-Kali: New concept and potential biological subgroup for relapsed or refractory AML