American Association for Cancer Research (AACR): Advancing the Frontiers of Cancer Science Since 1907

In 1907, a small group of eleven visionary scientists gathered in Washington, D.C. to take the first step in what would become a monumental journey—a journey to change the course of cancer research forever. From that pivotal moment, the American Association for Cancer Research (AACR) was born. What began as a passionate, determined group of doctors and researchers has now evolved into the world’s first and largest organization dedicated to advancing cancer research.

Today, with over 54,000 members in 130 countries and territories, AACR unites a diverse community of cancer researchers, clinicians, and advocates, all working toward the shared mission of preventing and curing all cancers. But this is not just a story of numbers—it’s a story about people, passion, and an unwavering commitment to change the future of cancer.

Source: AACR/X

The AACR’s Journey: From Humble Beginnings to Global Impact

The history of the AACR is a remarkable tale of determination, discovery, and growth. Founded by four surgeons, five pathologists, and two biochemists, the organization began as a small scientific society with a singular focus: cancer. Their first meeting in 1907 laid the groundwork for what would become a global hub of cancer research.

Fast forward to 1916, when the AACR launched The Journal of Cancer Research, marking a major milestone in cancer literature. This journal became a critical resource for researchers, and over the years, AACR’s annual meetings blossomed into one of the most important gatherings for sharing cutting-edge cancer research.

Through the years, the AACR has continued to lead the charge in transforming cancer science. Notable achievements include the launch of Cancer Research in 1941 and Clinical Cancer Research in 1995. The organization has also remained a staunch advocate for diversity in research and has established global partnerships that have enabled thousands of investigators worldwide to further the fight against cancer.

As AACR President, Dr. Lillian L. Siu, reflected on their journey:

“As we celebrate the anniversary of the founding of the AACR, we reflect on the remarkable progress made against cancer throughout our history, and we renew our commitment to save, extend, and enhance the lives of patients with cancer.”

Reflecting on History: Milestones that Shaped AACR’s Legacy

Here are some key moments in AACR’s rich history:

• 1907–1915: Founding Years – The inaugural scientific meeting took place in 1907 at Cornell University’s Loomis Laboratory, where nine research papers were presented.
• 1916–1939: Knowledge Dissemination – The Journal of Cancer Research was launched, making a significant contribution to cancer research.
• 1940–1963: Rapid Growth – The AACR grew significantly during this period, becoming a key player in cancer research. The first comprehensive history of the AACR was published in Cancer Research in 1961.
• 1964–1981: Emerging Leadership – In 1964, AACR helped found the American Society of Clinical Oncology (ASCO).
• 1982–1999: Expansion – The organization expanded its programs to meet the growing complexity of cancer research.
• 2000–Present: Leading the Charge – AACR established programs such as Minorities in Cancer Research (MICR) and launched the AACR Foundation for the Prevention and Cure of Cancer.

The AACR’s journey isn’t just a timeline of dates—it’s about the lives that have been changed, the breakthroughs that have happened, and the passion that continues to drive the mission.

The AACR’s storied history, spanning over a century, is rich with milestones and transformative achievements. Read the full narrative history on the AACR website.

AACR’s Mission: Turning Research into Action

At the heart of AACR’s mission is a simple, yet powerful goal: to prevent and cure cancer through innovative research, collaboration, and science. Their work spans the entire cancer research spectrum, from basic laboratory research to clinical trials, and from population studies to precision medicine. This comprehensive approach ensures that their findings translate into real-world solutions for patients.

The AACR Annual Meeting has become one of the most anticipated events on the cancer research calendar. Bringing together tens of thousands of scientists, clinicians, and advocates, it serves as a vital platform to share the latest breakthroughs and innovations, further accelerating progress against cancer.

Global Leadership: A Worldwide Movement

The AACR isn’t just a leader in the United States; it’s a global force in the fight against cancer. Today, its reach spans across 142 countries and territories, with members working in concert to tackle the worldwide scourge of cancer. Reflecting on this evolution, Dr. Margaret Foti, CEO of AACR, shared on Twitter:

“In 1907, the founding members of the AACR were based in the United States. Today, with members in 142 countries and territories, the AACR is a global organization that is dedicated to eradicating the global scourge of cancer.”

This statement speaks volumes about the AACR’s expansion into a global network, uniting researchers, clinicians, and advocates from all corners of the world, united by a shared mission.

CEO, Margaret Foti and President, Lillian Siu; Source: Margaret Foti/X

Supporting the Next Generation: A Future of Hope

Looking ahead, the AACR remains committed to nurturing early-career scientists and promoting diversity in research. Programs like AACR Project GENIE—an initiative that harnesses the power of big data to drive precision oncology—are helping to revolutionize the way cancer is understood and treated. Through its grants, fellowships, and mentoring programs, AACR continues to amplify the voices of those working on the frontlines of cancer research.

This support is vital, as it ensures that the next generation of cancer researchers has the tools, resources, and opportunities to make even greater strides toward a world without cancer.

Where Science Meets Hope

At its core, the story of AACR is one of hope—a hope fueled by the relentless pursuit of knowledge, the collaboration of brilliant minds, and the belief that, together, we can conquer cancer.

It’s a story of people—scientists driven by curiosity, doctors guided by compassion, patients powered by courage, and communities united by hope. Over the years, AACR has become more than just an organization; it’s a movement. A place where young researchers get their first chance to shine, where groundbreaking discoveries happen, where cancer survivors find their voice, and where advocates and clinicians work hand in hand to make a difference.

As Dr. Foti wisely said:

“AACR is where the cancer research community comes together—to learn, to share, and to move science forward for the benefit of patients.”

At AACR, every breakthrough made, every life touched, and every story shared brings us closer to a world where cancer is no longer a threat. Together, we believe in a future where the science of today brings the cures of tomorrow.

For more such stories and insights from the world of oncology, visit OncoDaily.

By: Md Foorquan Hashmi, MD, Sr. Editor, OncoDaily: India Bureau