Alireza Mansouri: Explaining Glioblastoma Treatments
Alireza Mansouri, Associate Professor at Penn State Health, shared a post on X:
“Explaining GBM treatments: Start with surgery – remove as much tumor as safely possible without hurting key functions (like speaking or moving). As a neurosurgeon, I use brain scans to map it out, GPS-like tools in the OR, and sometimes awake tests where patients name things or move. Safety first!
Why radiation? Tiny unseen cells can linger after surgery & cause regrowth. Targeted energy beams over weeks zap them – paired with other treatments for better results. Can cause tiredness, but we manage it!
Temozolomide (TMZ): Pill you take by mouth, not IV chemo. Messes with tumor growth instructions; usually skips severe nausea, hair loss, or immunity drops (check blood tests though). Taken with/after radiation.
Clinical trials: Where new hope comes in! Testing immunotherapy (body’s defenses vs. tumor, like vaccines or immune boosters), custom vaccines for longer survival, drug-radiation combos. Neurosurgery Trials make care personal – ask your doc if one’s a fit!”
Read More About Glioblastoma on Oncodaily.
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