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Fixed-Duration Acalabrutinib Combinations in Untreated Chronic Lymphocytic Leukemia
Leukemia/medlineplus.gov
Mar 5, 2025, 08:16

Fixed-Duration Acalabrutinib Combinations in Untreated Chronic Lymphocytic Leukemia

Fadi Haddad, Assistant Professor at The University of Texas MD Anderson Cancer Center, shared a paper Jennifer R. Brown and colleagues authored on X:

“AMPLIFY Ph 3 trial

867 patients, median age 61 yrs, ND CLL

No TP53/del17p, unmutated IGHV 59%

Acala+Ven x1 yr (AV) AV x1 yr + Obin x6 mo (AVO) Chemo-immunotherapy (CT)

3-year PFS: 77% AV versus 83% AVO versus 67% CT.”

Fixed-Duration Acalabrutinib Combinations in Untreated Chronic Lymphocytic Leukemia

Authors: Jennifer R. Brown et al.

Fixed-Duration Acalabrutinib Combinations in Untreated Chronic Lymphocytic Leukemia

acalabrutinib Alan Skarbnik Alessandra Tedeschi Andrew Aw Arnon Philip Kater Árpád Illés Barbara Eichhorst cancer Carolyn Owen Chronic lymphocytic leukemia (CLL) Daniel Lysak Jennifer R. Brown John F. Seymour Kara Miller Ki-Seong Eom Malgorzata Wach Marianne de Borja Martin Šimkovič Miguel Arturo Pavlovsky OncoDaily Oncology Paolo Ghia Ting Yu Veerendra Munugalavadla Wojciech Jurczak
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