Cancer treatments can activate dormant tumor cells in the lung triggering metastasis

Iván R. González, Medical Oncologist at Comprehensive Oncology Center, Hospital Ángeles Puebla, shared a post on X:

“Recent research reveals that cancer treatments can activate dormant tumor cells in the lung, triggering metastasis months or years after initial treatment.

• Disseminated tumor cells (DTCs) remaining dormant can awaken due to therapy-induced tissue damage.
• Post-treatment inflammation and changes in the microenvironment are crucial for this process.
• Developing strategies to inhibit this awakening is vital to reduce metastatic recurrence and enhance treatment effectiveness.Understanding how oncologic treatments can reactivate dormant tumor cells in the lung, triggering metastasis, is essential for improving clinical outcomes. Research into post-treatment inflammation and microenvironmental changes is pivotal in this context. Developing effective strategies to mitigate this risk is crucial to reduce recurrence and optimize cancer management.”

Source: Iván R. González/X