Photo taken from Erman Akkus/X
Jun 20, 2024, 06:54
Hereditary germline cancer variants in biliary tract cancer
Erman Akkus, Medical Oncology Fellow at Ankara University, shared on X:
“Hereditary germline cancer variants in biliary tract cancer
27 cancer-predisposing genes analysed in 1,292 BTC cases and 37,583 controls
5.5% had at least one pathogenic variant
BRCA1, BRCA2, APC, MSH6, PALB2
PALB2 were marginally associated
Ongoing preclinical and clinical studies in BTC targeting DDR.”
Source: Erman Akkus/X