Tanja Obradovic: One exciting novel approach is just about to enter clinical development
Tanja Obradovic, Vice President of Oncology Scientific Affairs at
“Cell therapy in the solid tumors has been challenging and numerous next generation options are attempting breakthrough. One exciting novel approach is just about to enter clinical development. MDG1015, a first-in-class, third generation T cell receptor engineered T cell (TCR-T) therapy targeting NY-ESO-1/ LAGE-1a (New York oesophageal squamous cell carcinoma 1 / L Antigen Family Member-1a), armored and enhanced with the PD1-41BB co-stimulatory switch protein (CSP) made by very innovative team at Medigene AG. PhI trail is planned for gastric cancer, ovarian cancer, myxoid/round cell liposarcoma and synovial sarcoma with IND/CTA filing targeted for 2H 2024. More on MDG1015 is just about to be presented at Immuno-Oncology Summit Europe in few days.”
Source: Tanja Obradovic/LinkedIn
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