Myriam Chalabi: First results of the CM8HW are out!

Myriam Chalabi shared a post on X/Twitter:

“First results of the CM8HW are out! Nivo/ipi vs chemo in 1st line dMMR mCRC. We knew it would be positive, but wow HR 0.21 for PFS and + across all subgroups. No crossing of the curves! Toxicity very manageable (don’t be scared of low dose ipi1).

Important note: >10% of patients misclassified as dMMR!”

Source: Myriam Chalabi/X

Myriam Chalabi is a Gastrointestinal Oncologist and clinician scientist at the Netherlands Cancer Institute in Amsterdam. In 2022 she was named one of the 11 early career researchers to watch by Nature Medicine. In 2023 she was awarded the ESMO José Baselga Fellowship for Clinician Scientists.