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Molecular profiling of sqNSCLC reveals high incidence of actionable genomic alterations among patients with no history of smoking
Jan 22, 2025, 10:25

Molecular profiling of sqNSCLC reveals high incidence of actionable genomic alterations among patients with no history of smoking

Yakup Ergün, Medical Oncologist at Antalya City Hospital, shared a post on X:

“Comprehensive profiling of sqNSCLC

AGAs were detected in 22.2% of never-smokers

Never-smokers with sqNSCLC had a significantly higher prevalence of actionable MET (9.5% vs 0.4%) and EGFR mutations (7.9% vs 0.4%) compared to ever-smokers.”

Comprehensive molecular profiling of squamous non-small cell lung cancer reveals high incidence of actionable genomic alterations among patients with no history of smoking

Authors: Joshua E. Reuss, Jacob Zaemes, Nishant Gandhi, Phillip Walker,  Sandip P. Patel, Joanne Xiu, Charu Aggarwal, Ari Vanderwalde, Suresh S. Ramalingam, Balazs Halmos, Stephen V. Liu

Molecular profiling of sqNSCLC reveals high incidence of actionable genomic alterations among patients with no history of smoking