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Erman Akkus: Downstaging of HCC before liver transplantation
Jan 20, 2025, 15:56

Erman Akkus: Downstaging of HCC before liver transplantation

Erman Akkus, Medical Oncology Fellow at Ankara University, shared a post about recent paper by Edison Xu et al. on X:

“Downstaging of HCC before liver transplantation.

Petients meeting UNOS-downstaging (DS) criteria vs. All-comers” (AC)
At 2 years from first local regional therapy: downstaging 82% vs 66%, p<0.001

In AC, Y-90 >TACE, 74% vs. 65%, p<0.001
5-year post-LT recurrence in AC 30% vs. 14%;p=0.02
5-year post-transplant survival was similar

In the era of immunotherapy?”

Downstaging of hepatocellular carcinoma before liver transplantation: Results from a national multi-center prospective cohort study

Authors: Edison Xu et al.

Erman akkus