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Ahmed Kotb: FLT3 Inhibitors choice in AML
myhematology.com
Jan 2, 2025, 16:48

Ahmed Kotb: FLT3 Inhibitors choice in AML

Ahmed Kotb, Hematologist and Bone marrow transplanter at King Faisal Specialist Hospital International Holding Company (KFSHI), shared a post on X:

“FLT3 Inhibitors choice in AML:

Midostaurin vs. Quizartinib

Midostaurin:

Targets FLT3-ITD & FLT3-TKD

QTc <500ms

Favored in males

maintenance post-chemotherapy

Quizartinib:

Targets FLT3-ITD only

QTc <450 ms

Favored in females, WBC ≥40, NPM1-mutated

maintenance post-alloTx.”

Ahmed Kotb: FLT3 Inhibitors choice in AML

Ahmed Kotb AML cancer fight against cancer FLT3 Global fight against cancer Grande Prairie midostaurin OncoDaily Oncology quizartinib
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