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Toni K. Choueiri: CLEAR study biomarker analysis is out
Dec 15, 2024, 14:52

Toni K. Choueiri: CLEAR study biomarker analysis is out

Toni K. Choueiri, Director of the Lank Center for Genitourinary (GU) Oncology at Dana-Farber Cancer Institute (DFCI), shared on X:

“CLEAR study biomarker analysis with Robert Motzer and friends is out in Annals of Oncology —thank you EIC Tom Powles for a flawless process!

Lenvatinib + Pembrolizumab improved ORR/PFS vs. sunitinib in aRCC, consistent across PD-L1, gene expression, mutations, subtypes. No predictive biomarker!”

Biomarker analyses from the phase 3 randomized CLEAR trial: Lenvatinib plus pembrolizumab versus sunitinib in advanced renal cell carcinoma

Authors: R.J. Motzer, C. Porta, M. Eto, T.E. Hutson, S.Y. Rha, J.R. Merchan, E. Winquist, H. Gurney, V. Grünwald, S. George, J. Markensohn, J.E. Burgents, R. Cristescu, P. Sachdev, Y. Narita, J. Huang, Z. Zhao, C.E. Okpara, Y. Minoshima, T.K. Choueiri

Toni K. Choueiri

Toni K. Choueiri is the Director of the Lank Center for Genitourinary (GU) Oncology at Dana-Farber Cancer Institute (DFCI), co-leader of the Kidney Cancer Program at Dana-Farber/Harvard Cancer Center, and the Jerome and Nancy Kohlberg Chair and Professor of Medicine at Harvard Medical School. As a medical oncologist, clinical trialist, and translational researcher, he specializes in treating genitourinary cancers (prostate, bladder, testis, and kidney cancer), with a focus on kidney cancer.