November, 2024
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PSADTime ≤6 months Identifies High-Risk BRPC Patients after Prostatectomy
Nov 28, 2024, 11:19

PSADTime ≤6 months Identifies High-Risk BRPC Patients after Prostatectomy

Ravi A Madan, Clinical researcher focused on Prostate Cancer at National Cancer Institute, shared on X:

“Since EMBARK data there is a need to define high risk BCR Prostate Cancer.

Best data I have seen comes from John Hopkins Medicine team.

Risk of mets at 5 years is only 26% for PSA DT 6-9 months. Significantly lower risk than DT 3-6 mos or DT under 3 mos.”

Prostatectomy

Mark C. Markowski, Genitourinary Oncologist, Associate Professor, Director of GU Oncology in the National Capital Region at Johns Hopkins SKCCC, shared this post on X, adding:

“Your natural history study with PSMA PET imaging will be incredibly important. We did not find an association between PSADT and a positive PSMA PET. To me this suggests that novel imaging may not inform who needs treatment. PSADT still the gold standard.”

Prostatectomy

PSA doubling time (PSADT) ≤6 months to identify a subgroup of men with biochemically-recurrent prostate cancer (BRPC) after prostatectomy (RP) at highest risk of distant metastasis (dMET).

Authors: Daniel L. Suzman, Jennifer Cullen, Bruce J. Trock, Yongmei Chen, Inger L. Rosner, Zhaoyong Feng, Emmanuel S. Antonarakis, Misop Han, Alan W. Partin, Lauren Hurwitz, Huai-Ching Kuo, David G.McLeod, and Mario A. Eisenberger

PSADTime ≤6 months Identifies High-Risk BRPC Patients after Prostatectomy