Aaron Goodman: What is an “M protein”
Aaron Goodman, Associate Professor of Medicine at the University of California, posted on X:
“What the hell is an ‘M protein‘?
Monoclonal immunoglobulin secreted by an abnormally expanded clone of plasma cells in an amount that is above the polyclonal immunoglobulin background.
M protein = Many words for same thing
•Paraprotein
•Monoclonal protein (M-protein)
•M-component
•M-spike M protein may contain
•Heavy + light chains (intact immunoglobulin)
•Light chains only (light chain myeloma, light chain deposition disease, AL amyloidosis)
•Heavy chains only (heavy chain deposition disease).”
Aaron Goodman is a Hematologist/ Oncologist and an Associate Professor of Medicine at the University of California, San Diego. He is a member of the National Comprehensive Cancer Network (NCCN) guideline committee for both cutaneous NHLs and T-cell NHLs. Dr. Goodman is a well-known physician-scientist, educator, advocate, and social media influencer.
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