Aaron Goodman posted the following on X:
“CMV drugs!
Ganciclovir
GCV-phos -> DNA
WBC
Foscarnet
Mimic of pyrophosphate interferes with exchange in DNA
Nephrotoxicity, electrolytes
Cidofovir CDV-phos -> DNA
Nephrotoxicity/Fanconi syndrome
Letermovir = PPx
Targets CMV DNA terminase (pUL56)
Limited toxicity.”
Source: Aaron Goodman/X
Aaron Goodman is a Hematologist/ Oncologist and an Associate Professor of Medicine at the University of California, San Diego. He is a member of the National Comprehensive Cancer Network (NCCN) guideline committee for both cutaneous NHLs and T-cell NHLs. Dr. Goodman is a well-known physician-scientist, educator, advocate, and social media influencer.