MSS/MSI-H testing needs to be done with colonoscopy biopsies

Aparna Raj Parikh shared a post by CRCTrialsChat on X:

“We do reflex testing with colonoscopy but unlike rectal where all patients see medical oncology and radation oncology and surgery   at diagnosis, we also have to get our surgeons to send us patients with colon ca before surgery.

Also, the small ihc/pcr discordance   bothers me as msi-h is a never miss.”

Quoting CRCTrialsChat’s post:

“MSS/MSI-H testing needs to be done with colonoscopy biopsies, so MSI-H patients know their status and don’t have surgeries 1st.”

Source: Aparna Raj Parikh /X and CRCTrialsChat/X

Aparna Raj Parikh is a GI oncologist, at Massachusetts General Hospital and associate professor at the Harvard Medical School. She has a long-standing background and interest in global health, having spent time in several African countries, Haiti and India. Most recently, at MGH, she co-founded and co-leads a program called POETIC (Program for Enhanced Training in Cancer (POETIC)). This fellowship exchange program, conducted in collaboration with Beth Israel Deaconess Medical Center Cancer Center and Lowell Schnipper, MD, trains clinical.