Jarushka Naidoo: Delighted to present the findings of the LECOMTE-PACIFIC study at ESMO24 Congress
Jarushka Naidoo shared a post on LinkedIn:
“Delighted to present the findings of the LECOMTE-PACIFIC study at the ESMO – European Society for Medical Oncology ESMO24 Congress, aiming to use radiomics for the early detection of pneumonitis in patients with stage III nsclc treated with chemo radiation followed by immunotherapy.
In this study, we:
- analyzed radiomic features of CT scans from pts who developed symptomatic pneumonitis v not from the Ph III PACIFIC trial
- we identified 2 radiomic features (reticulation volume/TLC and Lung volume) associated with pneumonitis
- we developed a 7 variable score together with clinical variables, with encouraging discriminative power for early detection of pneumonitis (AUC 0.78)
- next step, validation in additional datasets and optimization with high res CTs and CTs pre chemoRT.”
Source: Jarushka Naidoo/LinkedIn
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Dr. Jarushka Naidoo is a thoracic oncologist at the Beaumont Hospital Dublin (Ireland), Professor in RCSI and Adjunct Professor of Oncology at Johns Hopkins University. She currently serves as national lung cancer lead for Cancer Trials Ireland.
She serves on several international guideline panels including ASCO and SITC (Society of Immunotherapy for Cancer), and is an experienced clinical trialist- having developed and completed several investigator-initiated, industry-funded and cooperative group clinical trials.
She has received a number of grants including a young investigator award from the International Association for the Study of Lung Cancer (IASLC), Lung Cancer Foundation of America (LCFA), and a career development award from the National Institutes of Health (NIH) KL2-program. She is the IASLC Communications Committee Chair.
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