News Feed Opinion Blog Career Insight Dialogues Celebrities Oncolibrary
Positive Societies Drugs Stories History Cancer Center Near Me Cancer Types Immune Oncology Oncologist Near Me
December, 2024
December 2024
M T W T F S S
 1
2345678
9101112131415
16171819202122
23242526272829
3031  
Michael Rothenberg: A next generation BRAF Inhibitor shows promise in treatment refractory cancer patients
Photo taken from S. Michael Rothenberg/LinkedIn
Sep 9, 2024, 17:52

Michael Rothenberg: A next generation BRAF Inhibitor shows promise in treatment refractory cancer patients

Michael Rothenberg, Chief Medical Officer at I

“The Pfizer, Pfizer Boulder Research Unit, and academic collaborators’ clinical and translational work on PF-07799933 (ARRY-440) is out in the September issue of Cancer Discovery. A next-generation, brain-penetrant, pan-mutant BRAF-selective inhibitor, together with innovative and accelerated phase 1 clinical development with demonstrated efficacy in treatment-refractory cancer patients.”

A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with BRAF-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation 

Authors: Rona Yaeger, Meredith A. McKean, Rizwan Haq, J. Thaddeus Beck, Matthew H. Taylor, Jonathan E. Cohen, Daniel W. Bowles, Shirish M. Gadgeel, Catalin Mihalcioiu, Kyriakos P. Papadopoulos, Eli L. Diamond, Keren B. Sturtz, Gang Feng, Stefanie K. Drescher, Micaela B. Reddy, Bhaswati Sengupta, Arnab K. Maity, Suzy A. Brown, Anurag Singh, Eric N. Brown, Brian R. Baer, Jim Wong, Tung-Chung Mou, Wen-I Wu, Dean R. Kahn, Sunyana Gadal, Neal Rosen, John J. Gaudino, Patrice A. Lee, Dylan P. Hartley, S. Michael Rothenberg

Michael Rothenberg: A next generation BRAF Inhibitor shows promise in treatment refractory cancer patients

Source: Michael Rothenberg/LinkedIn

Anurag Singh Arnab K. Maity Bhaswati Sengupta BRAF-selective inhibitor Brian R. Baer cancer Cancer Discovery Catalin Mihalcioiu Daniel W. Bowles Dean R. Kahn Dylan P. Hartley Eli L. Diamond Eric N. Brown Gang Feng J. Thaddeus Beck Jim Wong John J. Gaudino Jonathan E. Cohen Keren B. Sturtz Kyriakos P Papadopoulos Matthew H. Taylor Meredith A. McKean Micaela B. Reddy Michael Rothenberg Neal Rosen OncoDaily Oncology Patrice A. Lee Rizwan Haq Rona Yaeger S. Michael Rothenberg Shirish M. Gadgeel Stefanie K. Drescher Sunyana Gadal Suzy A. Brown Tung-Chung Mou Wen-I Wu
Special Coverage
Blog
Dec 21, 2024, 14:10
Arif Kamal: Ensuring all people have access to the cancer navigation services that will help them live more and better days
Blog
Dec 21, 2024, 14:06
The Accelerate 2025 Annual Conference Agenda Is Here!
Blog
Dec 21, 2024, 14:03
Pioneer the future of discovery and innovation with a fully funded Bicentenary PhD Studentship at The University of Manchester
Blog
Dec 21, 2024, 14:00
NCI Division of Cancer Prevention - DHT Derived Biomarkers and COAs for Remote Monitoring and Endpoint Development
Blog
Dec 21, 2024, 13:51
The ESMO President Letter emphasises the importance of collective action to shape the future of oncology
Blog
Dec 21, 2024, 13:48
Overcoming recurrence: How research is bringing new hope for breast cancer patients - The Institute of Cancer Research
Blog
Dec 21, 2024, 13:46
IARC - Cancer Incidence in Five Continents, Vol XII
Blog
Dec 21, 2024, 13:43
National University Cancer Institute, Singapore clinicians had the exciting opportunity to present their work at the ESMO Asia 2024
Blog
Dec 21, 2024, 13:40
UICC - Welcoming the newest member, The World Hepatitis Alliance
Blog
Dec 21, 2024, 13:35
Pediatric Cancer and Blood Disorders Center of Armenia - Prioritizing the continuous education and knowledge exchange of the medical staff
Blog
Dec 21, 2024, 13:33
SIOP Europe - International Childhood Cancer Day 2025
Blog
Dec 21, 2024, 13:29
Canadian Cancer Society - How 5 organizations are working to take on cancer’s biggest issues