Denis Wirtz, Vice Provost of Research at Johns Hopkins University, shared on X:
“Macrophages are terrible at migrating. In contrast, their precursor cells – monocytes – are highly motile.
Monocytes exploit interleukin 6 (IL-6) secreted by cancer cells and themselves to migrate fast and promote cancer cell proliferation. More here.”
High-motility pro-tumorigenic monocytes drive macrophage enrichment in the tumor microenvironment
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Source: Denis Wirtz/X