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Photo taken from Denis Wirtz/X

Jul 30, 2024, 17:23

Denis Wirtz: Migrating monocytes in TME

Denis Wirtz, Vice Provost of Research at Johns Hopkins University, shared on X:

“Macrophages are terrible at migrating. In contrast, their precursor cells – monocytes – are highly motile.

Monocytes exploit interleukin 6 (IL-6) secreted by cancer cells and themselves to migrate fast and promote cancer cell proliferation. More here.”

High-motility pro-tumorigenic monocytes drive macrophage enrichment in the tumor microenvironment

Autors: Wenxuan Du, Bryan Zhou, André Forjaz, Sarah M. Shin, Fan Wu, Ashleigh J. Crawford, Praful R. Nair, Adrian C. Johnston, Hoku West-Foyle, Ashley Tang, Dongjoo Kim, Rong Fan, Ashley L. Kiemen, Pei-Hsun Wu, Jude M. Phillip, Won Jin Ho, David E. Sanin, Denis Wirtz

Migrating

Source: Denis Wirtz/X

Adrian C. Johnston André Forjaz Ashleigh J. Crawford Ashley L. Kiemen Ashley Tang Bryan Zhou cancer David E. Sanin Denis Wirtz Dongjoo Kim Fan Wu Hoku West-Foyle Jude M. Phillip monocytes OncoDaily Oncology Pei-Hsun Wu Praful R. Nair Rong Fan Sarah M. Shin Wenxuan Du Won Jin Ho

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