Two recent papers studying BRAF alterations in PCa
Recently two papers have been published about BRAF alterations in prostate cancer:
Unique Spectrum of Activating BRAF Alterations in Prostate Cancer.
Authors: Alex Chehrazi-Raffle, Hanna Tukachinsky, Eamon Toye, Smruthy Sivakumar, Alexa B. Schrock, Hannah E. Bergom, Hedyeh Ebrahimi, Sumanta Pal, Tanya Dorff, Neeraj Agarwal, Brandon A. Mahal, Geoffrey R. Oxnard, Justin Hwang, Emmanuel S. Antonarakis.
Targeting the multifaceted BRAF in cancer: New directions.
Authors: Eamon Toye, Alexander Chehrazi-Raffle, Justin Hwang, Emmanuel S. Antonarakis.
Emmanuel Antonarakis, Professor of Medicine at the University of Minnesota, who is co-author in both studies, shared a post on X:
”Congratulations Eamon Toye and Alex Chehrazi-Raffle on your 2 recent papers studying BRAF alterations in PCa. Unlike other BRAF-altered cancers, PCa is characterized by Class II muts and activating fusions, including AR-regulated BRAF fusions.”
Source: Emmanuel Antonarakis/X