Anand Patel: Myeloid neoplasms after MTX have features more similar to de-novo

Anand Patel, Assistant Professor and Director of the Inpatient Leukemia Service at the University of Chicago, shared a post on X/Twitter:

“We often discuss if myeloid neoplasms after MTX therapy have high-risk features/cytogenetics – this report found myeloid neoplasms after MTX have features more similar to de-novo disease than t-MN.”

Source: Anand Patel/X

Authors: Mihir D. Wechalekar, Lin-Pierre Zhao, Monika M. Kutyna, Lih En Hong, Joule Li, Kevin Hung, Hamish S. Scott, Anna Brown, Christopher C. Hahn, Karin Kassahn, Dariusz Ladon, David T. Yeung, Daniel Thomas, Mrinal Patnaik, Susanna Proudman, Lionel Ades, Mithun V. Shah, Chung H. Kok and Devendra K. Hiwase

Myeloid neoplasms arising after methotrexate therapy for autoimmune rheumatological diseases do not exhibit poor-risk molecular features