Wenchang Yue: Why Recurrence and Progression in Bladder Cancer Require Different Approaches
Wenchang Yue/X

Wenchang Yue: Why Recurrence and Progression in Bladder Cancer Require Different Approaches

Wenchang Yue, Postdoctoral Fellow at Mount Sinai Health System, shared on X:

“In bladder cancer, what’s the difference between recurrence and progression?

Recurrence is a tumor growing back without the grade or stage getting worse. Progression is moving in a more serious direction, typically from non-muscle-invasive to muscle-invasive. Recurrence is far more likely: even in low-risk disease it runs 10% to 35% over 5 years.

The two call for completely different handling: recurrence is managed within the existing framework, while progression means switching to a different volume to read (volume two).

So when you hear,

it grew back,

the first thing to ask is:

compared with last time, have the grade and stage changed?

You can also read:

Prognostic Value of Perioperative ctDNA Across Bladder Cancer Histologies

Wenchang Yue: Why Recurrence and Progression in Bladder Cancer Require Different Approaches