Wafik S. El-Deiry: Seeding Density–Dependent Drug Resistance Measured by ISDS Index
Wafik S. El-Deiry/brown.edu

Wafik S. El-Deiry: Seeding Density–Dependent Drug Resistance Measured by ISDS Index

Wafik S. El-Deiry, Director of Legorreta Cancer Center at Brown University and Chair of the WIN Consortium in Cancer Personalized Medicine, shared a post on X:

“Feature in April 9, 2026 Science Magazine looking at CTC clusters and their potential targeting as a strategy to treat metastasis.

The Eldeiry Lab has worked on CTC’s and recently discussed the targeting of CTC clusters in Punyamurtula et al. in 2023.”

Title: Cancer cell seeding density as a mechanism of chemotherapy resistance: a novel cancer cell density index based on IC50-Seeding Density Slope (ISDS) to assess chemosensitivity

Authors: Ujwal Punyamurtula, Thomas W Brown,  Shengliang Zhang, Andrew George, Wafik S El-Deiry

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Wafik S. El-Deiry

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