Roberto Ferrara, Medical Oncology Researcher at Vita-Salute San Raffaele University, shared a post on X:
“Binding PD-1 and VEGF does not mean only target neoangiogenis but also immune exhaustion. VEGF, like PD-1, is responsabile of T-cell exhaustion and double blockade means to deeply reinvigorates T-cells. In this setting, PD-L1 expression may loose its predictive power.”
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