Siddhartha Yadav, Associate Professor of Oncology and Consultant Medical Oncologist at the Mayo Clinic, shared a post on X about a recent article he co-authored with colleagues published in Gynecologic Oncology:
“What happens to patients with advanced ovarian cancer who do not undergo cytoreductive surgery?
Our data show that despite neoadjuvant chemotherapy with intent for interval surgery, approximately 25% are unable to proceed due to poor response to neoadjuvant chemotherapy or functional status decline, resulting in worse outcomes. We are designing risk-adaptive clinical trials with alternative regimens to improve rates of ICS- more to come soon. ”
Title: Real-world outcomes of neoadjuvant chemotherapy for advanced ovarian cancer: What happens to patients who never undergo surgery?
Authors: Kelly H. Bruce, Conway Xu, Rushi P. Shah, Michaela E. McGree, Angela J. Fought, Siddhartha Yadav, Carrie L. Langstraat, William A. Cliby, Amanika Kumar
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