Sara Coca Membribes, Clinical Research Fellow to Prof Powles at Barts Health NHS Trust, shared a post on X:
“New Annals Oncology review on the balance of ADC design. Some degree of linker instability may contribute to favorable pharmacology (SG, sacTMT) by balancing payload release, systemic exposure or clearance.
Congrats to Raffaele Colombo and coauthors!”
Title: Re-Evaluating Antibody–Drug Conjugate Linker Stability: Assessment, Interpretation, and Clinical Translation
Authors: R. Colombo, S. Seredick, S.D. Barnscher, J.R. Rich.
Read the full article on ESMO Annals of Oncology.
Other articles featuring Sara Coca Membribes on OncoDaily.
