Raffaele Colombo, Associate Director, Medicinal Chemistry at Zymeworks Inc, shared a post on X:
“Is ADC stability paramount to ADC success? How should stability be correctly assessed? What are some common assumptions and mistakes regarding ADC linker stability?
We tried to address these questions and more in our recent Annals of Oncology review!”
Giampaolo Bianchini, the leading specialist in breast oncology in the Department of Clinical Oncology at the San Raffaele Scientific Institute, shared a post by Raffaele Colombo, adding:
” Interested in ADCs? This is a must-read paper.
Congratulations Raffaele Colombo.”
Title: Re-Evaluating Antibody–Drug Conjugate Linker Stability: Assessment, Interpretation, and Clinical Translation
Authors: Raffaele Colombo, S. Seredick, S. D. Barnscher, J. R. Rich
Read the article: here.

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