Paolo Tarantino: Pan-Tumor Activity of Novel B7-H3 ADC SYS6043

Paolo Tarantino: Pan-Tumor Activity of Novel B7-H3 ADC SYS6043

Paolo Tarantino, Research Fellow Dana-Farber Cancer Institute and Harvard Medical Schoolpost, shared a post on X:

The new Enhertu?

Presented at ASCO26, the FIH phase 1/2 trial of SYS6043 (n=627) shows impressive activity across a wide variety of tumor types. Mostly hematologic and GI tox, though ILD was observed, despite Fc engineering. No relationship of efficacy with B7H3 expression.”

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