Myriam Chalabi, Medical Oncologist and Cancer Immunotherapy researcher, Gastrointestinal Oncology at Antoni van Leeuwenhoek, shared on LinkedIn:
“Early successes in colon immunotherapy – Nature Medicine
January 6th, 2026
For Nature Medicine’s 30-year anniversary, I was granted the opportunity to write a Turning Points essay on our 2020 paper, ‘Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers’, the first published results from the NICHE trial.
A personal story behind the paper, on how this publication impacted my career, but more importantly medicine and the patients. Thankful to all those who cheered me on and persevered with me, and to all the patients who entrusted us with their care.
Turning point definition: a time at which a decisive change in a situation occurs, especially one with beneficial results.
NICHE was definitely decisive and beneficial for many patients and their loved ones, for those treating and taking care of them, and for me personally. Published today in Nature Medicine, to kick off the year with good news and hoping for widespread good news for many more patients.
Read the full piece.
Original NICHE publication.”
More posts from Myriam Chalabi on OncoDaily.