Myeloma Paper of the Day

Myeloma Paper of the Day, November 7th, Suggested by Robert Orlowski

Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:

“Myeloma Paper of the Day:

T-cells near Waldenström-like tumors in mice are disrupted, tumor B-cells adopt an immunoregulatory phenotype evoking regulatory B-cells, ibrutinib decreases B-cell activation/expansion and partially reverses T-cell depletion.”

Title: Uncovering regulatory B-cell features associated with regulatory T-cell expansion and global T-cell exhaustion in Waldenström macroglobulinemia Myd88L252P-like lymphoplasmacytic lymphomas

Authors: Quentin Lemasson, Maxime Tabaud, Ophélie Téteau, Bastien Carle, Mina Chabaud, Jean Feuillard, Nathalie Faumont, Christelle Vincent-Fabert

You can read the Full Article in HemaSphere.

Myeloma Paper of the Day, November 7th, Suggested by Robert Orlowski

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