Mark Hughes Foundation (MHF) Centre for Brain Cancer Research shared on LinkedIn:
“Congratulations to Simin Zheng who won the Best Poster Award at the School of Biomedical Sciences and Pharmacy ECR/HDR Researcher Showcase. Her poster, Using Drug Repurposing to Target DNA Repair in Brain Cancer, outlined the following research: Glioblastoma (GBM) is the most aggressive type of adult brain cancer and remains difficult to treat despite surgery, radiotherapy, and chemotherapy.
Simin’s research investigates whether FDA-approved drugs that can cross the blood-brain barrier can be repurposed to improve the effectiveness of current GBM treatments.
In this study, they identified a promising candidate that reduced tumour cell growth, enhanced the response to radiotherapy and temozolomide, and altered DNA damage response signalling in patient-derived GBM models. These findings support further investigation of this approach as a potential strategy to improve outcomes for patients with GBM.
This work is very exciting and we’re so proud of everything that Simin is achieving in this field. With Paul Tooney, Nikola Bowden, Mike Fay, Kelsey Maddison.”
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