Livnat Jerby, Assistant Professor at Stanford University, posted on X:
“Excited to share our paper on engineering spatially targeted immune cells is now out in Nature Immunology.
CRISPR activation screens reveal that engineering metabolite-sensing NK and T cells provides programmable mechanisms to target solid tumors.
Congrats to Young Min Kim, Mike Tsai, and the team!
Thanks to Ovarian Cancer Research Alliance, Stanford Cancer Institute, Allen Institute, BWFUND, Chan Zuckerberg Biohub Network, National Human Genome Research Institute, Tull Family Foundation, Stanford Cancer Biology, Stanford Genetics and Stanford Medicine for the support.”
Title: Engineering NK and T cells with metabolite-sensing receptors to target solid tumors
Authors: Young-Min Kim, Min K. Tsai, Chang Sun, Olivia Laveroni, Reece Villarin Akana, Kristen Frombach and Livnat Jerby
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