Karamvir Yadav: Obesity and Diabetes Don’t Weaken Avelumab Benefit in Urothelial Cancer
Karamvir Yadav/X

Karamvir Yadav: Obesity and Diabetes Don’t Weaken Avelumab Benefit in Urothelial Cancer

Karamvir Yadav, Medical Oncologist at Harish Renova Hospital, shared a post on X:

JAVELIN Bladder 100 update.

Do obesity or diabetes reduce the benefit of maintenance immunotherapy in advanced urothelial carcinoma?

This long-term analysis says no.

  •  BMI ≥30 kg/m²: OS HR 0.77
  • Diabetes mellitus: OS HR 0.60
  • Consistent PFS benefit
  • No new safety signals

Avelumab maintenance remains an effective option after platinum-based chemotherapy, regardless of these common cardiometabolic comorbidities.”

Karamvir Yadav

Other articles featuring Karamvir Yadav and Avelumab Maintenance on OncoDaily.