Karamvir Yadav, Medical Oncologist at Harish Renova Hospital, shared a post on X:
“Would you add immunotherapy upfront to prevent chemotherapy resistance?
The TROPHAMET trial reports a 96.2% durable remission rate and no relapses at 41 months with avelumab + methotrexate in low-risk GTT. Rare disease.
Big signal. Worth watching closely.”

Title: Avelumab Plus Methotrexate for Gestational Trophoblastic Tumors
Authors: Benoit You, Jean-Pierre Lotz, Pierre Descargues, Florence Joly, Thibault De La Motte Rouge, Coriolan Lebreton, Laurence Gladieff, Philippe Follana, Mathieu Jamelot, Jerome Massardier, Touria Hajri, Adrien Msika, Marine Alves-Ferreira, Sylvie Bin, Carole Langlois-Jacques, Fabien Subtil, Adeline Roux, Christophe Desauw, Magali Provansal, Verane Schwiertz, Francois Golfier, Pierre-Adrien Bolze
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