Jeremy Bellaiche, Medical Oncologist, Co-Founder and Executive Director of MedNews Week, shared a post on LinkedIn:
“Excited to share the episode 13 of The Translational Edge with Yan Leyfman, MD exclusively on Shuf! From Stomach to Beta Cells: Regenerating Insulin Producers via Gastric Stem Cells
- For people with insulin-dependent diabetes, the loss or dysfunction of pancreatic beta cells is the core issue
- The researchers used human embryonic stem cell–derived cells to generate miniature, simplified versions of stomach tissue grown in culture.
- This is regenerative medicine at a deep, systems level — not just patching deficits, but reprogramming tissue identity.
- Rather than lifelong insulin injections or donor islets, patients might someday receive a one-time regenerative transplantation of autologous, reprogrammed tissue that produces insulin endogenously.
- Translating to human clinical therapy will require rigorous additional work
Other articles featuring Jeremy Bellaiche on OncoDaily.