Hong Jae Chon, Director of Cancer Center, CHA Bundang Medical Center, shared a post on X:
“ICI moving to earlier stage of primary liver cancer Journal of Hepatology.
- TACE + ICI: PFS improved across 4 RCTs, but OS immature
- Neoadjuvant HCC: CARES-09 positive (HR 0.59)
- Adjuvant HCC: IMbrave050 and KEYNOTE-937 negative
- Adjuvant BTC: no RCT yet.”

Title: Integrating systemic therapy in the earlier stages of liver cancer
Authors: Julien Edeline, Ming Kuang, Maria Reig, Valérie Vilgrain
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