Giuseppe Caruso, Gynecology Oncology Specialist at European Institute of Oncology, shared a post on LinkedIn:
“Proud of this outstanding team and especially pleased to share my first publication as a supervisor.
Our review, ‘Hold the Line: Local Control Strategies in Oligoprogressive Gynecologic Cancers During Systemic Therapy’, explores a rapidly evolving and highly relevant topic in gynecologic oncology: how local treatments may help maintain the benefit of ongoing effective systemic therapies (often in maintenance setting) in selected patients with oligoprogressive disease.
- Locoregional therapy may help control oligoprogression during otherwise effective systemic treatment, prolong NEST-FS, and preserve quality of life
- Strongest evidence supports this strategy in PARPi-treated ovarian cancer
- Data in endometrial and cervical cancers remain limited and exploratory
- Combining SBRT with targeted therapies shows promise but lacks standardization
- Prospective trials are needed to refine selection and treatment sequencing
This is such a timely and engaging topic in gynecologic oncology. Significant advances have been made in recent years – especially for ovarian cancer patients receiving PARPis – but many questions remain open. Excited to contribute to this ongoing discussion and looking forward to the next steps in research.”
Title: Hold the line: Local control strategies in oligoprogressive gynecologic cancers during systemic therapy
Authors: Filippo Casaccia, Giordanoa, Roberta Lazzaric, Gabriella Macchiad, Stefano Durantec, Claudia Marchettie, Anna Fagottie, Isabelle Ray-Coquardg, Barbara Alicja Jereczek-Fossab, Nicoletta Colomboa, Giuseppe Caruso
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