Voices
Giannis Mountzios: The Biggest RWD Cohort on T-DXd in HER2-Mutant NSCLC
Giannis Mountzios/LinkedIn

Giannis Mountzios: The Biggest RWD Cohort on T-DXd in HER2-Mutant NSCLC

Giannis Mountzios, Director of the 4th Oncology Department and Clinical Trials Unit at Henry Dunant Hospital Center, shared a post on LinkedIn:

“TRACER/HERTras study just out in Journal of Thoracic Oncology by Illini et al. the biggest RWD cohort on T-DXd in HER2mut NSCLC:

  • N= 168, brain mets=27, 1L=18
  • ORR=54.8%, DCR=88.7% accross LoT
  • mPFS=7.2 m, mOS= 18.3m
  • icORR= 74.1%, incl icCRR=25.9%
  • G>=3 TRAEsin 32%, ILD=14%

Happy to have co-ordinated the project on behalf of Greece.”

 

Title: Systemic and Intracranial Efficacy and Safety of Trastuzumab Deruxtecan in Patients With HER2-Mutant NSCLC Across Treatment Lines: Evidence From the TRACER/HERTras Real-World Cohort

Authors: Oliver Illini, Anna-Carina Hund, Hans-Georg Kopp, Mor Moskovitz, Giannis Mountzios, Wolfgang M. Brueckl, Martin Früh, Marie-Elisabeth Leßmann, Petros Christopoulos, Albrecht Stenzinger, Michael Thomas, Roni Gillis, Nir Peled, Fabian Acker, Alfredo Addeo, Andriani Charpidou, Christian Grohé, Horst-Dieter Hummel, Laetitia Mauti, Sacha I. Rothschild, Sabine Schmid, Christian Schumann, Damien Urban, Robert Wurm, Simon Ekman, Marcus Skribek, Franziska Glanemann, Marcel Wiesweg, Christoph Jakob Ackermann, Sofia Agelaki, Petra Hoffknecht, Marko Jakopović, Jens Kern, David König, Katharina Kostenzer, Cornelia Kropf-Sanchen, Eckart Laack, David Lang, Laurenz Nagl, Georg Pall, Martin Reck, Waleed Kian, Anna T. Allemann, Jürgen Alt, David Araújo, Hanibal Bohnenberger, Alexandros Bokas, Hannah Fabikan, Krainer-Jacobs Julie, Christoph Weinlinger, Adrianus Johannes de Langen, Evangelos Georgios Fergadis, Rieke Fischer, Elena Fountzilas, Patrizia Froesch, Nikolaj Frost, Frank Griesinger, Franziska Jordan, Charisios Karanikiotis, Barbara Kiesewetter, Ippokratis Korantzis, Andrea Lopes Machado, Panagiota Economopoulou, Arnold Pilz, Patrick Reimann, Achim Rittmeyer, Akram Saad, Konstantinos Samitas, Karsten Schulmann, Riyaz Shah, Jan Alexander Stratmann, Hossein Taghizadeh, Kai Tammoscheit, Amanda Tufman, Jan-Phillip Weber, Ewald Wöll, Arschang Valipour, Tobias R. Overbeck, Maximilian J. Hochmair

Read the Full Article.

Giannis Mountzios: The Biggest RWD Cohort on T-DXd in HER2-Mutant NSCLC

Other articles about lung caner on OncoDaily.

Achim Rittmeyer Adrianus Johannes de Langen Akram Saad Albrecht Stenzinger Alexandros Bokas Alfredo Addeo Amanda Tufman Andrea Lopes Machado Andriani Charpidou Anna T. Allemann Anna-Carina Hund Arnold Pilz Arschang Valipour Barbara Kiesewetter cancer Charisios Karanikiotis Christian Grohe Christian Schumann Christoph Jakob Ackermann Christoph Weinlinger Cornelia Kropf-Sanchen Damien Urban David Araújo David König David Lang Eckart Laack Elena Fountzilas Evangelos Georgios Fergadis Ewald Wöll Fabian Acker Frank Griesinger Franziska Glanemann Franziska Jordan Georg Pall Giannis Mountzios Hanibal Bohnenberger Hannah Fabikan Hans-Georg Kopp Horst-Dieter Hummel Hossein Taghizadeh Ippokratis Korantzis Jan Alexander Stratmann Jan-Phillip Weber Jens Kern Jürgen Alt Kai Tammoscheit Karsten Schulmann Katharina Kostenzer Konstantinos Samitas Krainer-Jacobs Julie Laetitia Mauti Laurenz Nagl Lung cancer Marcel Wiesweg Marcus Skribek Marie-Elisabeth Leßmann Marko Jakopović Martin Früh Martin Reck Maximilian J. Hochmair Michael Thomas Mor Moskovitz Nikolaj Frost Nir Peled NSCLC Oliver Illini OncoDaily Oncology Panagiota Economopoulou Patrick Reimann Patrizia Froesch Petra Hoffknecht Petros Christopoulos Rieke Fischer Riyaz Shah Robert Wurm Roni Gillis Sabine Schmid Sacha I. Rothschild Simon Ekman Sofia Agelaki Tobias R. Overbeck TRACER/HERTras study Waleed Kian Wolfgang M. Brueckl