Erdinç Nayır, Associate Professor of Internal Medicine and Medical Oncology at VM Medicalpark Mersin Hospital, shared a post on X:
“Baseline fatigue matters in cancer care
Baseline fatigue predicts higher treatment toxicity.
7,086 patients (17 phase II–III trials)
With baseline fatigue:
- ~2× higher risk of severe toxicity
- ↑ life-threatening toxicity
- ↑ treatment-related death
More fatigue = more risk → Up to 5× higher fatal toxicity
Clinical message: Baseline fatigue may be a simple, powerful risk marker before starting cancer treatment.”
Title: Baseline Fatigue and Severe Toxic Effects in Patients With Cancer Receiving Systemic Therapy
Authors: Joseph Unger, Michael Fisch, Salene Jones, N. Lynn Henry, Dawn L. Hershman
Read the Full Article in JAMA Oncology.

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