Enrique Grande, Medical Oncology Department Director at Quironsalud Madrid, Adjunct Professor at The University of Texas MD Anderson Cancer Center, shared a post on X:
“Histological subtypes of urothelial carcinoma – micropapillary, plasmacytoid, sarcomatoid, squamous – don’t fit the one-size-fits-all treatment paradigm.
Each carries distinct biology, is often understaged on TURBT, and shows variable response to standard systemic therapy.”
Title: Histological Subtypes and Divergent Differentiation of Urothelial Carcinoma: Histology, Genomics, and Management Implications
Authors: Can Aydogdu, Laura Bukavina, Liang Cheng, Hikmat A. Al-Ahmadie, Omar Alhalabi, Jason R. Brown, Antonio Lopez-Beltran, Petros Grivas, Clara Hwang, G. Daniel Grass, Ashish M. Kamat, Jonathan Chatzkel, Omar Mian, Andrea Necchi, Jeff Ross, Andrea B. Apolo, Philippe E. Spiess, Roger Li.

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