Charles Jiang and Ilyas Sahin: COVID mRNA Vaccination and Immunotherapy Outcomes
Charles Jiang and Ilyas Sahin

Charles Jiang and Ilyas Sahin: COVID mRNA Vaccination and Immunotherapy Outcomes

Charles Jiang, Medical Oncologist at UT Southwestern Medical Center, shared a post on X by Ilyas Sahin, Medical Oncologist at Massachusetts General Hospital, adding:

“Good chance to actually explain what ITB (immortal time bias) is, because it shows up everywhere in oncology RWD and most readers slide past it.

Simple definition: a stretch of follow-up during which a pt cannot, by design, have the outcome event. that time is ‘immortal’.”

Quoting Ilyas Sahin’s post:

“Should cancer patients on immunotherapy get the COVID mRNA vaccine? New French study  at Annals Oncology, 30,898 patients: yes. 9% lower risk of death when given within 3 months of starting a PD-(L)1 inhibitor.

Consistent across lung, melanoma, head and neck, kidney. Smaller than the Nature paper (2025), but tighter methodology and 30x more patients.”

Charles Jiang

Other articles featuring Ilyas Sahin on OncoDaily.

Medically reviewed May 21, 2026 by Mariam Khachatryan, MD