Charles Jiang and Ilyas Sahin: COVID mRNA Vaccination and Immunotherapy Outcomes
Charles Jiang and Ilyas Sahin

Charles Jiang and Ilyas Sahin: COVID mRNA Vaccination and Immunotherapy Outcomes

Charles Jiang, Medical Oncologist at UT Southwestern Medical Center, shared a post on X by Ilyas Sahin, Medical Oncologist at Massachusetts General Hospital, adding:

“Good chance to actually explain what ITB (immortal time bias) is, because it shows up everywhere in oncology RWD and most readers slide past it.

Simple definition: a stretch of follow-up during which a pt cannot, by design, have the outcome event. that time is ‘immortal’.”

Quoting Ilyas Sahin’s post:

“Should cancer patients on immunotherapy get the COVID mRNA vaccine? New French study  at Annals Oncology, 30,898 patients: yes. 9% lower risk of death when given within 3 months of starting a PD-(L)1 inhibitor.

Consistent across lung, melanoma, head and neck, kidney. Smaller than the Nature paper (2025), but tighter methodology and 30x more patients.”

Charles Jiang

Other articles featuring Ilyas Sahin on OncoDaily.