Cassio Murilo T Hidalgo Filho, Medical Oncology Fellow at the ICESP, shared a post by Hidehito Horinouchi, Assistant Chief of the National Cancer Center Hospital on X, adding:
”Thank you for sharing our review, Dr. Horinouchi.
We hope this work provides a useful framework to understand primary and acquired resistance to ICIs in NSCLC and emerging strategies to improve durable benefit.”
Quoting Hidehito Horinouchi‘s post:
”Overcoming primary and acquired resistance to ICI in NSCLC.
Key: Impaired antigen present, T-cell exhaustion and TME remodeling
Next-gen ICIs, epigen modul and metabolic agents against STK11/KEAP1.”
Title: Overcoming Primary and Acquired Resistance to Immunotherapy in Non–Small Cell Lung Cancer: Mechanisms, Challenges, and Emerging Strategies
Authors: Cassio Murilo Hidalgo-Filho, Valentina Santo, Eleonora Gariazzo, Mihaela Aldea, Federica Pecci, François-Xavier Danlos, Gilberto de Castro Junior, Biagio
Read The Full Article on the Journal of Clinical Oncology.
Other Articles Featuring Cassio Murilo T Hidalgo Filho and Hidehito Horinouchi on OncoDaily.