Bishoy Faltas, Chief Research Officer at the Englander Institute for Precision Medicine, shared on X:
“Nature recently published the largest compendium of next-generation patient-derived cancer models, including several bladder cancer models, some that were contributed by our team at WCM Englander Institute for Precision Medicine.
Building these models is only the first step. We’re now combining patient-derived organoids with AI to create ‘bio-digital avatars’ that may one day help predict treatment responses. CBS News recently featured this work.”
Title: A compendium of next-generation patient-derived models for diverse cancers
Authors: Dina ElHarouni, Mushriq Al-Jazrawe, Seongmin Choi, Merve Dede, Toshinori Hinoue, Sean A. Misek, Heeju Noh, Luca Zanella, Yuen-Yi Tseng, Hayley E. Francies, Dennis Plenker, Cindy W. Kyi, Julyann Perez-Mayoral, Megan J. Stine, Eva Tonsing-Carter, Rachana Agarwal, Jean Claude Zenklusen, James M. Clinton, Jennifer M. Shelton, Timothy R. Chu, William F. Hooper, Xavi Loinaz, Paula Keskula, Jordan Tagle, Peyton C. Kuhlers, Bahar Tercan, Sylvia F. Boj, Alessandro Vasciaveo, Lorenzo Tomassoni, James M. Crawford, Shawna Walsh, Claire Sinai, Sonam Bhatia, Priya Sridevi, Hardik Patel, Maria Antonietta Cerone, The HCMI Network, Kyle Ellrott, Calvin J. Kuo, Olivier Elemento, Semir Beyaz, Vincenzo Corbo, David L. Spector, Rameen Beroukhim, Martin L. Ferguson, Andrew D. Cherniack, Peter W. Laird, Nicolas Robine, Andrew McPherson, Katherine A. Hoadley, Mathew J. Garnett, David A. Tuveson, Andrea Califano, Paul T. Spellman, Keith L. Ligon, Daniela S. Gerhard, Louis M. Staudt, Jesse S. Boehm