Balazs Halmos: The Patient With A Broken Heart – Complex Lung Cancer Case With Cardiac Invasion
Balazs Halmos/doctors.montefioreeinstein.org

Balazs Halmos: The Patient With A Broken Heart – Complex Lung Cancer Case With Cardiac Invasion

Balazs Halmos, Professor of Medicine at Montefiore Health System, shared a post on X:

The patient with a broken heart.

Patient in mid 60s with past smoking history presented with chest discomfort and dyspnea.

Evaluation with CTA showed no PE but demonstrated a very large LUL mass with direct extension into mediastinum and L atrium and additional R sided lung lesions c/w st4 disease.

Cardiac MR and ECHO confirm a mobile mass in L atrium contiguous w LUL mass. Path shows lung adenoca, PD-L1 TPS score >90%, ctDNA+ for K-Ras G12C.

Tumor board review: surg/IR interventions not feasible, XRT likely not safe/effective, chemo – concern as to heme tox with heart invaded. Patient started on single agent IO.”

Balazs Halmos

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Medically reviewed Apr 6, 2026 by Mariam Khachatryan, MD