Anirban Maitra, Director of the Perlmutter Cancer Center, shared a post on X:
“Are two Pancreatic Cancers in the organ independent lesions or clonally related. Work by Eileen M O’Reilly and colleagues suggests that most are related lesions because of intra-pancreatic spread. These often have indolent biological features (KRAS SMAD4 WT).”
Title: Dual pancreatic carcinomas: clonally related or independent primaries?
Authors: Joshua D. Schoenfeld, Vignesh Ravichandran, Zeynep Tarcan, Hulya Sahin-Ozkan, Allison L. Richards, Nadeem Bilani, Joanne F. Chou, Catherine A. O’Connor, David McManamon, Anna M. Varghese, Fergus Keane, Michael I. D’Angelica, William R. Jarnagin, Jeffrey Drebin, Diane Reidy-Lagunes, Alice C. Wei, Sree B. Chalasani, Fiyinfolu Balogun, Wungki Park, Kenneth H. Yu, Kevin Soares, Mark T. A. Donoghue, Christine Iacobuzio-Donahue, Zsofia K. Stadler, Marinela Capanu, Olca Basturk and Eileen M. O’Reilly
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