Ahmet Dirican, Professor of Medical Oncology at Medicana International İzmir Hospital, shared a post on LinkedIn:
“Early-onset cancers are rising. But we are still asking the wrong questions.
- Current risk models are insufficient.
- Genetics alone cannot explain it.
- The exposome is highly complex.
We need a new framework: Cancer = a tissue ecosystem disease.
Three emerging models:
- Tissue ecosystem.
- Biological state.
- Dynamic preventability.
The future (my perspective): NGS + electronic health records (EHR) + AI + exposome
Oncology is evolving. From treatment – to prediction and prevention.”
Title: Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers
Authors: Mengyao Shi, Gary J. Patti, Marc J. Gunter, Ramaswamy Govindan, Iris Lansdorp-Vogelaar, Ting Wang, Jeffrey P. Townsend, Graham A. Colditz, Yasmine Belkaid, Yin Cao
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