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Mario Balsa: PIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma
Mario Balsa/LinkedIn

Mario Balsa: PIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma

Mario Balsa, Medical Oncology Resident at Catalan Institute of Oncology, shared a post on X:

“PIK3CA mutations in early-onset appendiceal adenocarcinoma. (n=200)

EOAC (<50y) vs LOAC (≥50y): higher PIK3CA mutations (17.1% vs 7.7%; OR 2.65)

Validated in GENIE cohort (12.3% vs 5.9%)

PIK3CA mutations seen in metastatic disease (11.8%)

Independently associated with worse OS (HR 2.62)

It is not just about age…it’s about who’s PI3K-ing the survival curve”

Title:PIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma

Authors: Princy Gupta, Rushabh Gujarathi, Lu Qiao, Elizabeth L. Godfrey, Kurt S. Schultz, Samuel D. Butensky, Justin M. Bader, Raghav Sundar, Michael Cecchini, Ardaman Shergill, Jason M. Sheltzer, Kiran K. Turaga

Read the full paper.

Mario Balsa: PIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma

Other articles featuring Mario Balsa on OncoDaily.

appendiceal adenocarcinoma Ardaman Shergill cancer Elizabeth L. Godfrey Jason M. Sheltzer Justin M. Bader Kiran K. Turaga Kurt S. Schultz Lu Qiao Mario Balsa Michael Cecchini OncoDaily Oncology Princy Gupta Raghav Sundar Rushabh Gujarathi Samuel D. Butensky