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Kohei Shitara: Happy to report biomarkers in DESTINIY GC01 at Nature Medicine
Photo of Kohei Shitara taken from X/Twitter
May 16, 2024, 09:09

Kohei Shitara: Happy to report biomarkers in DESTINIY GC01 at Nature Medicine

Kohei Shitara, Medical oncologist at National Cancer Center Hospital East, Japan shared a post on X:

“Happy to report biomarkers in DESTINIY GC01 at Nature Medicine. Trastuzumab Deruxtecan (T-DXd), response high if ctDNA+ while still activity observed in negative patients. Response regardless of KRAS, HER2, PIK3CA mutation. Decrease response in other RTKamp+. HER2 loss or topo1mt on PD.”

Kohei Shitara: Happy to report biomarkers in DESTINIY GC01 at Nature Medicine

Further Reading.
Source: Kohei Shitara/X

cancer ctDNA DESTINIY GC01 HER2 HER2 loss Japan Kohei shitara KRAS National Cancer Center Hospital East Nature Medicine OncoDaily Oncology PIK3CA mutation RTKamp+ topo1mt Trastuzumab Deruxtecan (T-DXd)
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