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Hidden Risks: BRCA Mutations and Breast Implants – CancerWorld

CancerWorld/LinkedIn

Aug 25, 2025, 14:15

Hidden Risks: BRCA Mutations and Breast Implants – CancerWorld

CancerWorld shared a post on LinkedIn:

“Hidden Risks: BRCA Mutations and Breast Implants

A recent study published in Blood Advances has revealed a significant link between BRCA mutations and the risk of developing breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). The study found that women with BRCA1/BRCA2 mutations who have textured breast implants face a 16-fold higher risk of developing BIA-ALCL compared to those without the mutations.

This study, led by researchers at Memorial Sloan Kettering Cancer Center, is the first prospective cohort study to track long-term outcomes in women with breast implants and a genetic predisposition to cancer.

With an estimated 2-5 million women worldwide still living with textured implants (which were recalled in 2019), these findings emphasize the urgent need for awareness and action.

Why it matters: This discovery broadens the cancer risks associated with BRCA mutations, which traditionally focus on breast and ovarian cancers, now highlighting implant-associated lymphomas as an additional concern.

Key takeaway: Survivors and patients should report their implant history, consider BRCA testing, and consult with healthcare providers to better understand the long-term risks associated with implants.

Read the full article.”

Yeva Margaryan, Managing Editor at CancerWorld, shared a post by CancerWorld, adding:

“Women with BRCA1/BRCA2 mutations who receive textured breast implants face a 16-fold higher risk of developing breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) compared to those without these mutations.”

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