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Tiago Cordeiro Felismino: Exploring the Role of Neutrophil-to-Lymphocyte Ratio in Advanced HCC Treatment
Aug 21, 2025, 14:41

Tiago Cordeiro Felismino: Exploring the Role of Neutrophil-to-Lymphocyte Ratio in Advanced HCC Treatment

Tiago Cordeiro Felismino, Chief at A.C.Camargo Cancer Center, shared a post on LinkedIn:

“Liver tumors, particularly hepatocellular carcinoma (HCC), are on the rise in Western countries, largely due to metabolic liver diseases.
The advent of immunotherapy has revolutionized advanced HCC treatment, significantly improving response rates and survival.
Still, about 20–40% of patients do not benefit, and to date, there are no validated biomarkers to identify this group.

Interestingly, a simple test — the complete blood count — may provide a clue. The Neutrophil-to-Lymphocyte Ratio (NLR) can help identify patients less likely to respond to immunotherapy.

Our group has recently shown this in a published study.”

Title: Neutrophil-to-Lymphocyte Ratio (NLR) as a Predictive Biomarker in Advanced Hepatocellular Carcinoma Treated with First-Line Immunotherapy

Authors: Tiago Felismino, Luanna Martins, Matheus Barroso, Daniela Carvalho, Angelo Brito, Claudia Maccali, Felipe Coimbra

Read the Full Article.

Tiago Cordeiro Felismino

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